Research

ORBION

The High-Resolution Multi-Pressure
Chemical Ionization Mass Spectrometer

Wherever science takes you.
Orbion delivers revolutionary performance in the lab or the field.

‣ Superior Resolving Power _{120,000 - 240,000 for clear molecular separation}

‣ Fast Polarity and Reagent Switching
_{Switch in seconds without compromising results}

‣ Sub-ppt Detection Limits
_{Confidently detect trace-level compounds}

‣ Maintenance-Free Solid Reagents
_{Fewer interventions. Consistent uptime.}

‣ Wide chemical coverage
_{VOCs · Amines · Acids · HOMs}_‍Ready to push the boundaries of analytical power?

Ionization

We pioneered fast polarity and reagent switching, extending it to multi-pressure ionization and introduced an entirely new class of reagents.

This provides highly selective, dual-pressure ion–molecule chemistry across a wide range of compounds—from trace gases to multifunctional organics—all captured in real time under ambient conditions.

MION2

Sampling

Our modular sampling platform enables flexible, unified workflows for gas-phase analysis, filter desorption, and online particle desorption—all within a single framework.

This adaptability supports both real-time and integrated sampling across laboratory and field deployments, extending chemical access from volatile gases to semi-volatile and particulate species.

Integrated System

Orbion combines high-resolution mass spectrometry, multi-mode ionization, and automated data handling into a single integrated and validated platform.

‍Designed for reliability and simplicity, it delivers molecular insight with minimal maintenance and setup.
‍
Download brochure here.

Solid Performance

A single Multi-Pressure CIMS system operating with solid reagents reveals a wide array of α-pinene oxidation products—across volatilities and functionalities—with remarkable sensitivity and stability.

‍By merging solid reagent delivery with multi-pressure ionization, we achieve comprehensive, field-ready performance in a single configuration.

Download webinar slides here.

Resources

Application Note: Rapid, Ultra sensitive Detection of Atmospheric Organonitrates

Organonitrates play a pivotal role in atmospheric chemistry: they regulate the NOₓ budget, drive secondary organic aerosol formation, and act as reservoirs for long-range nitrogen transport. Measuring these compounds at ultra-trace levels in humid, chemically complex air remains a significant analytical challenge.

Analytical Chemistry: Uronium Enables Sustainable Ultrasensitive Detection of Amines and Semivolatiles

Karsa researchers, together with partners in Helsinki and Tampere, have published in Analytical Chemistry a new method for sustainable, ultrasensitive detection of amines and semivolatiles. Using X-ray desorbed solid urea, the team achieved attomole-level sensitivity with stable operation across humidity conditions with all solid-state reagents.

White paper: The Next Decade of Atmospheric Science Will Be Driven by High-er Resolution

This white paper explains how insufficient resolution leads to ambiguity—and how new high-resolution mass spectrometry is essential for identifying what truly matters in air chemistry.

Mobile Orbitrap Mass Spectrometry: Stability and Performance in Motion

Historically, Orbitrap mass spectrometers have been considered large, power-intensive, and lab-bound instruments -- but times have changed!

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News

Orbion Launch: Website Updated and Brochure Now Live

30.10.2025

Research

Today we are formally launching Orbion, the fully integrated High Resolution Multi-Pressure Chemical Ionization (MPCI) mass spectrometer platform for air analysis. Orbion combines high-resolution detection, broad chemical coverage, and field-ready operation in a single cohesive system. The brochure is now available to download.

Karsa unveils ORBION: a pan‑molecular air analyzer

3.9.2025

Research

University of Helsinki team to deploy ORBION at CERN’s CLOUD chamber to map atmospheric chemistry in real-time.

Karsa Showcases Ionization Innovations at EAC 2025 in Lecce

1.9.2025

Research

Karsa is attending the European Aerosol Conference 2025 in Lecce, Italy, where we are presenting new developments in High Resolution Chemical Ionization Mass Spectrometry for aerosol research—and hosting a user get-together to connect with the MION Orbitrap community.

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